EFFEXOR XR® (venlafaxine HCl) | Safety Info

With the EFFEXOR XR Choice Card, eligible patients can get

EFFEXOR XR for just $1 a day or less*

It is free to sign up and
easy to get started!

Already have a card? Activate it here.

Patients may pay as little as $4 a month, depending on insurance. Learn more.

You pay $4 if you have:
  • Commercial/private insurance with an out-of-pocket expense of $130 or less for a 30-day supply of EFFEXOR XR.
You pay $30 if you have:
  • Other commercial/private insurance,
  • Medicare Part D,  or 
  • no insurance.

You may pay less by receiving the generic.

Patients with Medicare Part D must agree not to use any prescription benefits to purchase EFFEXOR XR.

If you have questions about the EFFEXOR XR Choice Card, please call 1-855-488-0749. A live customer service representative will be available 24 hours Monday through Friday, Saturday 8 am-7 pm ET, and Sunday 9 am-5 pm ET.

EFFEXOR XR is available in different dosage strengths (37.5 mg, 75 mg, and 150 mg).

Indications

EFFEXOR XR® (venlafaxine HCl) Extended-Release Capsules are indicated for the treatment, in adults, of Depression, Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), and Panic Disorder (PD) with or without agoraphobia.

Important Safety Information

Suicidality and Antidepressant Drugs

Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, teens, and young adults. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior. EFFEXOR XR is not approved for use in children and teens.

  • Do not take EFFEXOR XR if you currently take, or have taken within the last 14 days, any medicine known as an MAOI such as linezolid or methylene blue. Do not take an MAOI within 7 days of stopping EFFEXOR XR. Ask your doctor or pharmacist if you are not sure if your medicine is an MAOI.
  • All patients taking antidepressants should be watched closely for signs that their condition is getting worse or that they are becoming suicidal, especially when they first start therapy, or when their dose is increased or decreased. Patients should also be watched for becoming agitated, irritable, hostile, aggressive, impulsive, or restless. Such symptoms should be reported to the patient’s doctor right away.
  • Before starting EFFEXOR XR, tell your doctor if you’re taking or plan to take any prescription or over-the-counter drugs, including migraine headache medication, herbal preparations, and nutritional supplements, to avoid a potentially life-threatening condition.
  • EFFEXOR XR may raise blood pressure in some patients. Your blood pressure should be controlled before starting treatment and should be monitored regularly.
  • Taking EFFEXOR XR with aspirin, nonsteroidal anti-inflammatory drugs, warfarin, or other drugs that affect coagulation may increase the risk of bleeding events.
  • Some people are at risk for visual problems such as eye pain, changes in vision, or swelling or redness around the eye. You may want to undergo an eye examination to see if you are at risk and get preventative treatment if you are.
  • EFFEXOR XR should be used with caution if you have risk factors for a disturbance of the electrical activity of the heart known as QT/QTc prolongation or you are using concomitantly other drugs which prolong the QTc interval.
  • When people suddenly stop using or quickly lower their daily dose of EFFEXOR XR, discontinuation symptoms may occur. Talk to your doctor before discontinuing or reducing your dose of EFFEXOR XR.
  • Pregnant or nursing women shouldn’t take any antidepressant without consulting their doctor.
  • Until you see how EFFEXOR XR affects you, be careful doing such activities as driving a car or operating machinery. Avoid drinking alcohol while taking EFFEXOR XR.
  • In clinical studies, the most common side effects with EFFEXOR XR (reported in at least 10% of patients and at least twice as often as with placebo) were constipation, dizziness, dry mouth, insomnia, loss of appetite, nausea, nervousness, sexual side effects, sleepiness, sweating, and weakness.

Patients should always ask their doctors for medical advice about adverse events.

You may report an adverse event related to Pfizer products by calling 1-800-438-1985 (US only). If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly. The FDA has established a reporting service known as MedWatch where health care professionals and consumers can report serious problems they suspect may be associated with the drugs and medical devices they prescribe, dispense, or use. Visit MedWatch or call 1-800-FDA-1088.

Please see full Prescribing Information, including Boxed Warning, and Medication Guide for EFFEXOR XR.

Terms and Conditions

By using the EFFEXOR XR Choice Card (the "Card"), you attest that you meet the eligibility criteria and will comply with the Terms and Conditions described below:

You will pay $4 for a 30-day supply (30 tablets) if: you use commercial/private insurance and your out-of-pocket expense for a 30-day supply of brand-name EFFEXOR XR
is $130 or less.

You will pay $30 for a 30-day supply (30 tablets) if: you do not use prescription health coverage to purchase your brand-name EFFEXOR XR under this program or you use commercial/private insurance and your out-of-pocket expense for a 30-day supply of brand-name EFFEXOR XR is $130 or more. In addition:

  • a) Medicare Part D patients may participate in this Card Program, but cannot use any part of their Medicare Part D prescription benefit for EFFEXOR XR during the term of this offer
  • b) Out-of-pocket expenditures under this Card Program cannot be applied towards a patient’s Medicare Part D true out of pocket (TrOOP) expenses
  • c) Patients participating in this category cannot seek reimbursement for a purchase of EFFEXOR XR from any third party insurance entity during the term of this offer

This offer is not valid for prescriptions that are eligible to be reimbursed, in whole or in part, by Medicaid or other federal or state healthcare programs (including any state prescription drug assistance programs and the Government Health Insurance Plan available in Puerto Rico [formerly known as "La Reforma de Salud"]).

For all eligible patients, you can only qualify for up to $2500 of savings per calendar year. After a maximum of $2500, you will pay usual monthly out-of-pocket costs.

This Card cannot be combined with any other rebate/coupon, free trial, discount, prescription savings card, or similar offer for the specified prescription.

The Card will be accepted only at participating pharmacies.

This Card is not health insurance.

Offer valid only in the U.S. and Puerto Rico, but not for Massachusetts residents or where otherwise prohibited by law.

The Card is limited to 1 use per person per month during this offering period and is not transferable. It is illegal to sell, purchase, trade, or counterfeit, or offer to sell, purchase, trade, or counterfeit this Card.

Pfizer reserves the right to rescind, revoke or amend the Card Program without notice at any time.

You must be 18 or older to participate in this Program.

Card Program expires December 31, 2016.

No membership fees.

For questions about this card, please call 1-855-488-0749, visit EffexorXR.com or write to the address below.

For reimbursement when using mail order, mail copy of original pharmacy receipt (cash register receipt NOT valid) with product name, date and amount circled to:

EFFEXOR XR Choice Card
14001 Weston Parkway, Suite 103
Cary, NC 27513-9967

Be sure to include a copy of the front of your Choice Card, your name and mailing address.