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  • IndicationsEFFEXOR XR® (venlafaxine HCl) extended-release capsules are a prescription medicine indicated for the treatment, in adults, of Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), and Panic Disorder (PD) with or without agoraphobia.
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  • Prescribing Information & BOXED WARNING
  • Medication Guide
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The information provided in EFFEXORXRHCP.com is intended only for healthcare professionals in the United States.

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YOU MAY BE ELIGIBLE FOR THE EFFEXOR XR SAVINGS CARD IF...

  • You have insurance that:
    • Is provided by your employer or directly purchased by you
    • Is not Medicare, Medicaid, or any other state/federal health insurance
  • You are uninsured
  • You are 18 or older

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LEARN MORE ABOUT EFFEXOR XR

  • Taking EFFEXOR XR
  • How to Get Brand-Name EFFEXOR XR
  • Safety & Possible Side Effects
Scroll for Important Safety Information and Indications

IMPORTANT SAFETY INFORMATION

Suicidality and Antidepressant Drugs

Antidepressants increased the risk of suicidal thinking and behavior (suicidality) in children, teens, and young adults compared to placebo. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior. EFFEXOR XR is not approved for use in children and teens.

Do not take EFFEXOR XR if you:

  • Are allergic to EFFEXOR XR or any of the ingredients in EFFEXOR XR
  • Have uncontrolled angle-closure glaucoma
  • Currently take, or have taken within the last 14 days, any medicine known as a monoamine oxidase inhibitor (MAOI) such as linezolid or methylene blue. Do not take an MAOI within 7 days of stopping EFFEXOR XR. Ask your doctor or pharmacist if you are not sure if your medicine is an MAOI

    All patients taking antidepressants should be watched closely for signs that their condition is getting worse or that they are becoming suicidal, especially when they first start therapy, or when their dose is increased or decreased. Patients should also be watched for becoming agitated, irritable, hostile, aggressive, impulsive, or restless. Such symptoms should be reported to the patient's doctor right away.

    Before taking EFFEXOR XR, tell your doctor and pharmacist about all prescription and over-the-counter medications and supplements you take or plan to take, including those to treat migraines or psychiatric disorders (including other antidepressants or amphetamines) to avoid a potentially life-threatening condition called serotonin syndrome.

    EFFEXOR XR may raise blood pressure in some patients. Your blood pressure should be controlled before starting treatment and should be monitored regularly.

    Taking EFFEXOR XR with aspirin, nonsteroidal anti-inflammatory drugs, warfarin, or other blood thinners may increase the risk of bleeding events.

    Some people are at risk for visual problems such as eye pain, changes in vision, or swelling or redness around the eye. You may want to undergo an eye examination to see if you are at risk and get preventative treatment if you are.

    Taking serotonin and norepinephrine reuptake inhibitors (SNRIs), including EFFEXOR XR, may cause sexual problems.

    Do not stop EFFEXOR XR without first talking to your healthcare provider. When people suddenly stop using or quickly lower their daily dose of EFFEXOR XR, serious discontinuation symptoms may occur. These symptoms can be severe and last for a long time.

    Pregnant or nursing women shouldn't take any antidepressant without consulting their doctor.

    Until you see how EFFEXOR XR affects you, be careful doing such activities as driving a car or operating machinery. Avoid drinking alcohol while taking EFFEXOR XR.

    In clinical studies, the most common side effects with EFFEXOR XR (reported in at least 5% of patients and at least twice as often as with placebo) were constipation, dizziness, dry mouth, insomnia, loss of appetite, nausea, nervousness, sexual side effects, sleepiness, sweating, and weakness.

  • EFFEXOR XR is available as 37.5 mg, 75 mg and 150 mg capsules.

    INDICATIONS

    EFFEXOR XR extended-release capsules are a prescription medicine indicated for the treatment, in adults, of Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), and Panic Disorder (PD) with or without agoraphobia.

    Please see Full Prescribing Information, including BOXED WARNING and Medication Guide.
Important Safety Information and Indications

Suicidality and Antidepressant Drugs

Antidepressants increased the risk of suicidal thinking and behavior (suicidality) in children, teens, and young adults compared to placebo. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior. EFFEXOR XR is not approved for use in children and teens.

Do not take EFFEXOR XR if you:

  • Are allergic to EFFEXOR XR or any of the ingredients in EFFEXOR XR
  • Have uncontrolled angle-closure glaucoma
  • Currently take, or have taken within the last 14 days, any medicine known as a monoamine oxidase inhibitor (MAOI) such as linezolid or methylene blue. Do not take an MAOI within 7 days of stopping EFFEXOR XR. Ask your doctor or pharmacist if you are not sure if your medicine is an MAOI

All patients taking antidepressants should be watched closely for signs that their condition is getting worse or that they are becoming suicidal, especially when they first start therapy, or when their dose is increased or decreased. Patients should also be watched for becoming agitated, irritable, hostile, aggressive, impulsive, or restless. Such symptoms should be reported to the patient's doctor right away.

Before taking EFFEXOR XR, tell your doctor and pharmacist about all prescription and over-the-counter medications and supplements you take or plan to take, including those to treat migraines or psychiatric disorders (including other antidepressants or amphetamines) to avoid a potentially life-threatening condition called serotonin syndrome.

EFFEXOR XR may raise blood pressure in some patients. Your blood pressure should be controlled before starting treatment and should be monitored regularly.

Taking EFFEXOR XR with aspirin, nonsteroidal anti-inflammatory drugs, warfarin, or other blood thinners may increase the risk of bleeding events.

Some people are at risk for visual problems, such as eye pain, changes in vision, or swelling or redness around the eye. You may want to undergo an eye examination to see if you are at risk and get preventative treatment if you are.

Taking serotonin and norepinephrine reuptake inhibitors (SNRIs), including EFFEXOR XR, may cause sexual problems.

Do not stop EFFEXOR XR without first talking to your healthcare provider. When people suddenly stop using or quickly lower their daily dose of EFFEXOR XR, serious discontinuation symptoms may occur. These symptoms can be severe and last for a long time.

Pregnant or nursing women shouldn't take any antidepressant without consulting their doctor.

Until you see how EFFEXOR XR affects you, be careful doing such activities as driving a car or operating machinery. Avoid drinking alcohol while taking EFFEXOR XR.

In clinical studies, the most common side effects with EFFEXOR XR (reported in at least 5% of patients and at least twice as often as with placebo) were constipation, dizziness, dry mouth, insomnia, loss of appetite, nausea, nervousness, sexual side effects, sleepiness, sweating, and weakness.

EFFEXOR XR is available as 37.5 mg, 75 mg and 150 mg capsules.

INDICATIONS

EFFEXOR XR extended-release capsules are a prescription medicine indicated for the treatment, in adults, of Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), and Panic Disorder (PD) with or without agoraphobia.

Please see Full Prescribing Information, including BOXED WARNING and Medication Guide.

EFFEXOR XR SAVINGS CARD TERMS AND CONDITIONS

By participating in the EFFEXOR XR Savings Offer Program, you acknowledge that you currently meet the eligibility criteria and will comply with the terms and conditions described below:

  • This Savings Offer is not valid for prescriptions that are reimbursed, in whole or in part, by Medicaid, Medicare, TRICARE, Veterans Affairs healthcare, or any other federal or state healthcare program (including any state prescription drug assistance program), or the Government Health Insurance Plan available in Puerto Rico (formerly known as “La Reforma de Salud”)
  • The value of this Savings Offer is limited to $150 per use or the amount of your co-pay, whichever is less
  • This Savings Offer is not valid when the entire cost of your prescription drug is eligible to be reimbursed by your private insurance plans or other health or pharmacy benefit programs
  • You must deduct the savings received under this program from any reimbursement request submitted to your insurance plan, either directly by you or on your behalf
  • Eligible patients may pay a minimum of $4 per monthly prescription fill. By using this Savings Offer, eligible patients may receive a savings of up to $150 per fill off their co-pay or out-of-pocket costs. This Savings Offer is available for a maximum savings of $1,800 per year ($150 per month x 12 months). This Savings Offer may limit your prescription cost to $4, subject to a maximum $150 monthly benefit. Thus, if your co-pay or out-of-pocket cost is more than $150, you will save $150 off of your co-pay or total out-of-pocket costs. [Example: If your co-pay or out-of-pocket costs are $175, you will pay $25 ($175 – $150 = $25).] If your co-pay or out-of-pocket costs are no more than $150, you pay $4. For a mail-order 3-month prescription, your total maximum savings will be $450 ($150 x 3)
  • You must be 18 years of age or older to redeem this Savings Offer
  • Patients who are enrolled in Medicare, Medicaid, or another state or federal healthcare program may use this Savings Offer if paying for the prescription covered by this Savings Offer outside of their government insurance benefit, and no claim is submitted to Medicare, Medicaid, or any federal or state healthcare program. Such patients must not apply any out-of-pocket expenses incurred using this Savings Offer toward any government insurance benefit out-of-pocket spending calculations, such as Medicare Part D true out-of-pocket (TrOOP) costs
  • You are responsible for reporting use of this Savings Offer to any private insurer, health plan, or other third party who pays for or reimburses any part of the prescription filled using this Savings Offer, as may be required. You should not use this Savings Offer if your insurer or health plan prohibits use of manufacturer Savings Offers
  • This Savings Offer is not valid (i) for Massachusetts residents or (ii) for California residents whose prescriptions are covered, in whole or in part, by third-party insurance
  • This Savings Offer is not valid where prohibited by law
  • This Savings Offer is not valid for purchases of prescriptions discounted under the 340B drug pricing program
  • This Savings Offer cannot be combined with any other rebate/coupon, free trial, or similar offer for the specified prescription
  • This Savings Offer will be accepted only at participating pharmacies
  • This Savings Offer is not health insurance
  • This Savings Offer is good only in the U.S. and Puerto Rico
  • This Savings Offer is limited to 1 per person during this offering period and is not transferable
  • This Savings Offer may not be redeemed more than once per 30 days per patient
  • No other purchase is necessary
  • Data related to your redemption of this Savings Offer may be collected, analyzed, and shared with Viatris for market research and other purposes related to assessing Viatris' programs. Data shared with Viatris will be aggregated and de-identified; it will be combined with data related to other Savings Offer redemptions and will not identify you
  • Viatris reserves the right to rescind, revoke, or amend the program without notice
  • No membership fees. This Savings Offer and Program expire on 12/31/2023
  • For help with the EFFEXOR XR Savings Offer, call 1-855-488-0750, visit EFFEXORXR.com, or write: Viatris, P.O. Box 2941, Mission, KS 66201

If your pharmacy does not participate, you may be able to submit a request for a rebate in connection with this Savings Offer. Pay for your EFFEXOR XR prescription and mail copy of original pharmacy receipt (cash register receipt NOT valid) with product name, date, and amount circled to: EFFEXOR XR Savings Offer, 2250 Perimeter Park Drive, Suite 300, Morrisville, NC 27560. Be sure to include a copy of the front of your EFFEXOR XR Savings Card, your name, and mailing address.

EFFEXOR XR is available by prescription only.

Patients should always ask their doctors for medical advice about adverse events.

You are encouraged to report adverse events related to Viatris products by calling 1-800-438-1985 (U.S. only). If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly. Visit http://www.fda.gov/MedWatch or call 1-800-FDA-1088.

This site is intended only for U.S. residents. The products discussed in this site may have different product labeling in different countries. The information provided is for educational purposes only and is not intended to replace discussions with a healthcare provider.

Important Safety Information and Indications
+-

Suicidality and Antidepressant Drugs

Antidepressants increased the risk of suicidal thinking and behavior (suicidality) in children, teens, and young adults compared to placebo. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior. Effexor XR is not approved for use in children and teens.

Do not take EFFEXOR XR if you:

  • Are allergic to Effexor XR or any of the ingredients in Effexor XR
  • Have uncontrolled angle-closure glaucoma
  • Currently take, or have taken within the last 14 days, any medicine known as a monoamine oxidase inhibitor (MAOI) such as linezolid or methylene blue. Do not take an MAOI within 7 days of stopping Effexor XR. Ask your doctor or pharmacist if you are not sure if your medicine is an MAOI

    All patients taking antidepressants should be watched closely for signs that their condition is getting worse or that they are becoming suicidal, especially when they first start therapy, or when their dose is increased or decreased. Patients should also be watched for becoming agitated, irritable, hostile, aggressive, impulsive, or restless. Such symptoms should be reported to the patient's doctor right away.

    Before taking Effexor XR, tell your doctor and pharmacist about all prescription and over-the-counter medications and supplements you take or plan to take, including those to treat migraines or psychiatric disorders (including other antidepressants or amphetamines) to avoid a potentially life-threatening condition called serotonin syndrome.

    Effexor XR may raise blood pressure in some patients. Your blood pressure should be controlled before starting treatment and should be monitored regularly.

    Taking Effexor XR with aspirin, nonsteroidal anti-inflammatory drugs, warfarin, or other blood thinners may increase the risk of bleeding events.

    Some people are at risk for visual problems such as eye pain, changes in vision, or swelling or redness around the eye. You may want to undergo an eye examination to see if you are at risk and get preventative treatment if you are.

    Taking serotonin and norepinephrine reuptake inhibitors (SNRIs), including Effexor XR, may cause sexual problems.

    Do not stop Effexor XR without first talking to your healthcare provider. When people suddenly stop using or quickly lower their daily dose of Effexor XR, serious discontinuation symptoms may occur and in some patients these symptoms can be severe and last for a long time.

    Pregnant or nursing women shouldn't take any antidepressant without consulting their doctor.

    Until you see how Effexor XR affects you, be careful doing such activities as driving a car or operating machinery. Avoid drinking alcohol while taking Effexor XR.

    In clinical studies, the most common side effects with Effexor XR (reported in at least 5% of patients and at least twice as often as with placebo) were constipation, dizziness, dry mouth, insomnia, loss of appetite, nausea, nervousness, sexual side effects, sleepiness, sweating, and weakness.

    INDICATIONS

    Effexor XR extended-release capsules are a prescription medicine indicated for the treatment, in adults, of Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), and Panic Disorder (PD) with or without agoraphobia.

    Please see Full Prescribing Information, including BOXED WARNING and Medication Guide.

Suicidality and Antidepressant Drugs

Antidepressants increased the risk of suicidal thinking and behavior (suicidality) in children, teens, and young adults compared to placebo. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior. Effexor XR is not approved for use in children and teens.

Do not take EFFEXOR XR if you:

  • Are allergic to Effexor XR or any of the ingredients in Effexor XR
  • Have uncontrolled angle-closure glaucoma
  • Currently take, or have taken within the last 14 days, any medicine known as a monoamine oxidase inhibitor (MAOI) such as linezolid or methylene blue. Do not take an MAOI within 7 days of stopping Effexor XR. Ask your doctor or pharmacist if you are not sure if your medicine is an MAOI

    All patients taking antidepressants should be watched closely for signs that their condition is getting worse or that they are becoming suicidal, especially when they first start therapy, or when their dose is increased or decreased. Patients should also be watched for becoming agitated, irritable, hostile, aggressive, impulsive, or restless. Such symptoms should be reported to the patient's doctor right away.

    Before taking Effexor XR, tell your doctor and pharmacist about all prescription and over-the-counter medications and supplements you take or plan to take, including those to treat migraines or psychiatric disorders (including other antidepressants or amphetamines) to avoid a potentially life-threatening condition called serotonin syndrome.

    Effexor XR may raise blood pressure in some patients. Your blood pressure should be controlled before starting treatment and should be monitored regularly.

    Taking Effexor XR with aspirin, nonsteroidal anti-inflammatory drugs, warfarin, or other blood thinners may increase the risk of bleeding events.

    Some people are at risk for visual problems such as eye pain, changes in vision, or swelling or redness around the eye. You may want to undergo an eye examination to see if you are at risk and get preventative treatment if you are.

    Taking serotonin and norepinephrine reuptake inhibitors (SNRIs), including Effexor XR, may cause sexual problems.

    Do not stop Effexor XR without first talking to your healthcare provider. When people suddenly stop using or quickly lower their daily dose of Effexor XR, serious discontinuation symptoms may occur and in some patients these symptoms can be severe and last for a long time.

    Pregnant or nursing women shouldn't take any antidepressant without consulting their doctor.

    Until you see how Effexor XR affects you, be careful doing such activities as driving a car or operating machinery. Avoid drinking alcohol while taking Effexor XR.

    In clinical studies, the most common side effects with Effexor XR (reported in at least 5% of patients and at least twice as often as with placebo) were constipation, dizziness, dry mouth, insomnia, loss of appetite, nausea, nervousness, sexual side effects, sleepiness, sweating, and weakness.

    INDICATIONS

    Effexor XR extended-release capsules are a prescription medicine indicated for the treatment, in adults, of Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), and Panic Disorder (PD) with or without agoraphobia.

    Please see Full Prescribing Information, including BOXED WARNING and Medication Guide.

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