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  • IndicationsEFFEXOR XR (venlafaxine extended-release) capsules are a prescription medicine used to treat adults with a certain type of depression called Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), or Panic Disorder (PD).
    It is not known if EFFEXOR XR is safe and effective for use in children.
  • Important Safety Information
  • Prescribing Information & BOXED WARNING
  • Medication Guide
  • Healthcare Professionals
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The website you are about to access is not owned or controlled by VIATRISTM. Links to other websites are provided as a convenience to users and the inclusion of any link does not imply the endorsement of the linked site by Viatris. Viatris accepts no responsibility for the content of any linked sites.

The information provided in EFFEXORXRHCP.com is intended only for healthcare professionals in the United States.

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IMPORTANT SAFETY INFORMATION

What is the most important information I should know about EFFEXOR XR?
EFFEXOR XR may cause serious side effects, including:

Increased risk of suicidal thoughts and actions: EFFEXOR XR may increase suicidal thoughts and actions in some children, adolescents, and young adults, especially within the first few months of treatment or when the dose is changed. EFFEXOR XR is not for use in children.

  • Depression or other serious mental illnesses are the most important causes of suicidal thoughts or actions.
  • Pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is started or when the dose is changed.
  • Call your healthcare provider right away to report new or sudden changes in mood, behavior, thoughts, or feelings.
  • Keep all follow-up visits with your healthcare provider as scheduled. Call your healthcare provider between visits as needed, especially if you have concerns about symptoms.

Call your healthcare provider or get emergency help right away if you or a family member have any of the following symptoms, especially if they are new, worse, or worry you:

  • attempts to commit suicide
  • thoughts about suicide or dying
  • acting aggressive, being angry, or violent
  • acting on dangerous impulses
  • new or worse depression
  • new or worse anxiety
  • panic attacks
  • feeling very agitated or restless
  • new or worse irritability
  • trouble sleeping
  • an extreme increase in activity or talking (mania)
  • other unusual changes in behavior or mood

Do not take EFFEXOR XR if you:

  • are allergic to venlafaxine hydrochloride, desvenlafaxine succinate, or any of the ingredients in EFFEXOR XR. See the end of this Medication Guide for a complete list of ingredients in EFFEXOR XR.
  • take a Monoamine Oxidase Inhibitor (MAOI)
  • have stopped taking an MAOI in the last 14 days
  • are being treated with the antibiotic linezolid or intravenous methylene blue

Ask your healthcare provider or pharmacist if you are not sure if you take an MAOI, including MAOIs such as linezolid or intravenous methylene blue.

Do not start taking an MAOI for at least 7 days after you stop treatment with EFFEXOR XR.

Before taking EFFEXOR XR tell your healthcare provider about all your medical conditions and all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. EFFEXOR XR and other medicines may affect each other causing possible serious side effects. EFFEXOR XR may affect the way other medicines work and other medicines may affect the way EFFEXOR XR works.

Do not start or stop any other medicines during treatment with EFFEXOR XR without first talking to your healthcare provider.

EFFEXOR XR may harm your unborn baby. Tell your healthcare provider if you are pregnant, plan to become pregnant, or think you are pregnant during treatment with EFFEXOR XR.

EFFEXOR XR may cause serious side effects, including:

  • See, “What is the most important information I should know about EFFEXOR XR?”
  • Serotonin syndrome. Taking EFFEXOR XR can cause a potentially life-threatening problem called serotonin syndrome. The risk of developing serotonin syndrome is increased when EFFEXOR XR is taken with certain other medicines. Stop taking EFFEXOR XR and call your healthcare provider or go to the nearest hospital emergency room right away if you have any of the following signs and symptoms of serotonin syndrome:
    • agitation
    • seeing or hearing things that are not real (hallucinations)
    • confusion
    • coma
    • fast heartbeat
    • changes in blood pressure
    • dizziness
    • sweating
    • flushing
    • high body temperature (hyperthermia)
    • tremors, stiff muscles, or muscle twitching
    • loss of coordination
    • seizures
    • nausea, vomiting, diarrhea
  • Increases in blood pressure. Your healthcare provider should check your blood pressure before starting treatment and regularly during treatment with EFFEXOR XR. If you have high blood pressure, it should be controlled before you start treatment with EFFEXOR XR.
  • Increased risk of bleeding. Taking EFFEXOR XR with aspirin, non-steroidal anti-inflammatory drugs (NSAIDs), or blood thinners may add to this risk. Tell your healthcare provider right away about any unusual bleeding or bruising.
  • Eye problems (angle-closure glaucoma). EFFEXOR XR may cause a certain type of eye problem called angle-closure glaucoma. You may want to undergo an eye examination to see if you are at risk and receive preventative treatment if you are. Call your healthcare provider if you have eye pain, changes in your vision, or swelling or redness in or around the eye.
  • Manic episodes. Manic episodes may happen in people with bipolar disorder who take EFFEXOR XR. Symptoms may include:
    • greatly increased energy
    • severe trouble sleeping
    • racing thoughts
    • reckless behavior
    • unusually grand ideas
    • excessive happiness or irritability
    • talking more or faster than usual
  • Discontinuation syndrome. Suddenly stopping EFFEXOR XR may cause you to have serious side effects. Your healthcare provider may want to decrease your dose slowly. Symptoms may include:
  • Seizures (convulsions).
  • Low sodium levels in your blood (hyponatremia). Low sodium levels can happen during treatment with EFFEXOR XR. Low sodium levels in your blood may be serious and may cause death. Elderly people may be at greater risk for this.
  • Lung problems. Some people who have taken the medicine venlafaxine which is the same kind of medicine as the medicine in EFFEXOR XR have had lung problems. Symptoms of lung problems include difficulty breathing, cough, or chest discomfort. Tell your healthcare provider right away if you have any of these symptoms
  • Sexual problems (dysfunction). Taking selective serotonin reuptake inhibitors (SNRIs), including EFFEXOR XR, may cause sexual problems.

Do not drive, or operate heavy machinery, or do other dangerous activities until you know how EFFEXOR XR affects you. EFFEXOR XR can make you drowsy.

You should not drink alcohol during treatment with EFFEXOR XR.

The most common side effects of EFFEXOR XR include:

  • nausea
  • sleepiness
  • dry mouth
  • male and female sexual problems
  • loss of appetite (anorexia)
  • sweating
  • constipation

These are not all the possible side effects of EFFEXOR XR. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

INDICATIONS

EFFEXOR XR (venlafaxine extended-release) capsules are a prescription medicine used to treat adults with a certain type of depression called Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), or Panic Disorder (PD).
It is not known if EFFEXOR XR is safe and effective for use in children.

Please see Full Prescribing Information, including BOXED WARNING and Medication Guide.

YOUR CARD HAS BEEN ACTIVATED

Make sure you take your card to the pharmacy so you may save on brand-name EFFEXOR XR.

*Terms and Conditions apply.

Effexor saving card

3 TIPS TO GET BRAND-NAME EFFEXOR XR

    • Rx DAW

      At your doctor's office:

      Ask your doctor to prescribe brand-name EFFEXOR XR and to indicate "DAW" (Dispense As Written)—or the language used in your state—on all of your EFFEXOR XR prescriptions, as appropriate.*

      *Language and requirements may vary based on your state's laws.

    • Rx Prescription

      At your pharmacy's drop-off:

      Tell the pharmacist that you want brand-name EFFEXOR XR—and be sure to use the EFFEXOR XR Savings Card if eligible.

    • Prescription Bottle

      At your pharmacy's pick-up:

      Check your pills to be sure they're brand-name EFFEXOR XR—not the generic—and also check that you've saved on your prescription if eligible.


      Download a Tip Sheet here.

    LEARN MORE ABOUT EFFEXOR XR

    • Taking EFFEXOR XR
    • How to Get Brand-Name EFFEXOR XR
    • Safety & Possible Side Effects
    Scroll for Important Safety Information and Indications

    IMPORTANT SAFETY INFORMATION

    collapsecollapsecollapse

    What is the most important information I should know about EFFEXOR XR?
    EFFEXOR XR may cause serious side effects, including:

    Increased risk of suicidal thoughts and actions: EFFEXOR XR may increase suicidal thoughts and actions in some children, adolescents, and young adults, especially within the first few months of treatment or when the dose is changed. EFFEXOR XR is not for use in children.

    • Depression or other serious mental illnesses are the most important causes of suicidal thoughts or actions.
    • Pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is started or when the dose is changed.
    • Call your healthcare provider right away to report new or sudden changes in mood, behavior, thoughts, or feelings.
    • Keep all follow-up visits with your healthcare provider as scheduled. Call your healthcare provider between visits as needed, especially if you have concerns about symptoms.

    Call your healthcare provider or get emergency help right away if you or a family member have any of the following symptoms, especially if they are new, worse, or worry you:

    • attempts to commit suicide
    • thoughts about suicide or dying
    • acting aggressive, being angry, or violent
    • acting on dangerous impulses
    • new or worse depression
    • new or worse anxiety
    • panic attacks
    • feeling very agitated or restless
    • new or worse irritability
    • trouble sleeping
    • an extreme increase in activity or talking (mania)
    • other unusual changes in behavior or mood

    Do not take EFFEXOR XR if you:

    • are allergic to venlafaxine hydrochloride, desvenlafaxine succinate, or any of the ingredients in EFFEXOR XR. See the end of this Medication Guide for a complete list of ingredients in EFFEXOR XR.
    • take a Monoamine Oxidase Inhibitor (MAOI)
    • have stopped taking an MAOI in the last 14 days
    • are being treated with the antibiotic linezolid or intravenous methylene blue

    Ask your healthcare provider or pharmacist if you are not sure if you take an MAOI, including MAOIs such as linezolid or intravenous methylene blue.

    Do not start taking an MAOI for at least 7 days after you stop treatment with EFFEXOR XR.

    Before taking EFFEXOR XR tell your healthcare provider about all your medical conditions and all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. EFFEXOR XR and other medicines may affect each other causing possible serious side effects. EFFEXOR XR may affect the way other medicines work and other medicines may affect the way EFFEXOR XR works.

    Do not start or stop any other medicines during treatment with EFFEXOR XR without first talking to your healthcare provider.

    EFFEXOR XR may harm your unborn baby. Tell your healthcare provider if you are pregnant, plan to become pregnant, or think you are pregnant during treatment with EFFEXOR XR.

    EFFEXOR XR may cause serious side effects, including:


    • See, “What is the most important information I should know about EFFEXOR XR?”
    • Serotonin syndrome. Taking EFFEXOR XR can cause a potentially life-threatening problem called serotonin syndrome. The risk of developing serotonin syndrome is increased when EFFEXOR XR is taken with certain other medicines. Stop taking EFFEXOR XR and call your healthcare provider or go to the nearest hospital emergency room right away if you have any of the following signs and symptoms of serotonin syndrome:
      • agitation
      • seeing or hearing things that are not real (hallucinations)
      • confusion
      • coma
      • fast heartbeat
      • changes in blood pressure
      • dizziness
      • sweating
      • flushing
      • high body temperature (hyperthermia)
      • tremors, stiff muscles, or muscle twitching
      • loss of coordination
      • seizures
      • nausea, vomiting, diarrhea
    • Increases in blood pressure. Your healthcare provider should check your blood pressure before starting treatment and regularly during treatment with EFFEXOR XR. If you have high blood pressure, it should be controlled before you start treatment with EFFEXOR XR.
    • Increased risk of bleeding. Taking EFFEXOR XR with aspirin, non-steroidal anti-inflammatory drugs (NSAIDs), or blood thinners may add to this risk. Tell your healthcare provider right away about any unusual bleeding or bruising.
    • Eye problems (angle-closure glaucoma). EFFEXOR XR may cause a certain type of eye problem called angle-closure glaucoma. You may want to undergo an eye examination to see if you are at risk and receive preventative treatment if you are. Call your healthcare provider if you have eye pain, changes in your vision, or swelling or redness in or around the eye.
    • Manic episodes. Manic episodes may happen in people with bipolar disorder who take EFFEXOR XR. Symptoms may include:
      • greatly increased energy
      • severe trouble sleeping
      • racing thoughts
      • reckless behavior
      • unusually grand ideas
      • excessive happiness or irritability
      • talking more or faster than usual
    • Discontinuation syndrome. Suddenly stopping EFFEXOR XR may cause you to have serious side effects. Your healthcare provider may want to decrease your dose slowly. Symptoms may include:
    • Seizures (convulsions).
    • Low sodium levels in your blood (hyponatremia). Low sodium levels can happen during treatment with EFFEXOR XR. Low sodium levels in your blood may be serious and may cause death. Elderly people may be at greater risk for this.
    • Lung problems. Some people who have taken the medicine venlafaxine which is the same kind of medicine as the medicine in EFFEXOR XR have had lung problems. Symptoms of lung problems include difficulty breathing, cough, or chest discomfort. Tell your healthcare provider right away if you have any of these symptoms
    • Sexual problems (dysfunction). Taking selective serotonin reuptake inhibitors (SNRIs), including EFFEXOR XR, may cause sexual problems.
     

    Do not drive, or operate heavy machinery, or do other dangerous activities until you know how EFFEXOR XR affects you. EFFEXOR XR can make you drowsy.

    You should not drink alcohol during treatment with EFFEXOR XR.

    The most common side effects of EFFEXOR XR include:

    • nausea
    • sleepiness
    • dry mouth
    • male and female sexual problems
    • loss of appetite (anorexia)
    • sweating
    • constipation

    These are not all the possible side effects of EFFEXOR XR. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    INDICATIONS

    EFFEXOR XR (venlafaxine extended-release) capsules are a prescription medicine used to treat adults with a certain type of depression called Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), or Panic Disorder (PD).
    It is not known if EFFEXOR XR is safe and effective for use in children.

    Please see Full Prescribing Information, including BOXED WARNING and Medication Guide.

    Important Safety Information and Indications

    What is the most important information I should know about EFFEXOR XR?
    EFFEXOR XR may cause serious side effects, including:

    Increased risk of suicidal thoughts and actions: EFFEXOR XR may increase suicidal thoughts and actions in some children, adolescents, and young adults, especially within the first few months of treatment or when the dose is changed. EFFEXOR XR is not for use in children.

    • Depression or other serious mental illnesses are the most important causes of suicidal thoughts or actions.
    • Pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is started or when the dose is changed.
    • Call your healthcare provider right away to report new or sudden changes in mood, behavior, thoughts, or feelings.
    • Keep all follow-up visits with your healthcare provider as scheduled. Call your healthcare provider between visits as needed, especially if you have concerns about symptoms.

    Call your healthcare provider or get emergency help right away if you or a family member have any of the following symptoms, especially if they are new, worse, or worry you:

    • attempts to commit suicide
    • thoughts about suicide or dying
    • acting aggressive, being angry, or violent
    • acting on dangerous impulses
    • new or worse depression
    • new or worse anxiety
    • panic attacks
    • feeling very agitated or restless
    • new or worse irritability
    • trouble sleeping
    • an extreme increase in activity or talking (mania)
    • other unusual changes in behavior or mood

    Do not take EFFEXOR XR if you:

    • are allergic to venlafaxine hydrochloride, desvenlafaxine succinate, or any of the ingredients in EFFEXOR XR. See the end of this Medication Guide for a complete list of ingredients in EFFEXOR XR.
    • take a Monoamine Oxidase Inhibitor (MAOI)
    • have stopped taking an MAOI in the last 14 days
    • are being treated with the antibiotic linezolid or intravenous methylene blue

    Ask your healthcare provider or pharmacist if you are not sure if you take an MAOI, including MAOIs such as linezolid or intravenous methylene blue.

    Do not start taking an MAOI for at least 7 days after you stop treatment with EFFEXOR XR.  

    Before taking EFFEXOR XR tell your healthcare provider about all your medical conditions and all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. EFFEXOR XR and other medicines may affect each other causing possible serious side effects. EFFEXOR XR may affect the way other medicines work and other medicines may affect the way EFFEXOR XR works.

    Do not start or stop any other medicines during treatment with EFFEXOR XR without first talking to your healthcare provider.

    EFFEXOR XR may harm your unborn baby. Tell your healthcare provider if you are pregnant, plan to become pregnant, or think you are pregnant during treatment with EFFEXOR XR.

    EFFEXOR XR may cause serious side effects, including:

    • See, “What is the most important information I should know about EFFEXOR XR?”
    • Serotonin syndrome. Taking EFFEXOR XR can cause a potentially life-threatening problem called serotonin syndrome. The risk of developing serotonin syndrome is increased when EFFEXOR XR is taken with certain other medicines. Stop taking EFFEXOR XR and call your healthcare provider or go to the nearest hospital emergency room right away if you have any of the following signs and symptoms of serotonin syndrome:

      • agitation
      • seeing or hearing things that are not real (hallucinations)
      • confusion
      • coma
      • fast heartbeat
      • changes in blood pressure
      • dizziness
      • sweating
      • flushing
      • high body temperature (hyperthermia)
      • tremors, stiff muscles, or muscle twitching
      • loss of coordination
      • seizures
      • nausea, vomiting, diarrhea
    • Increases in blood pressure. Your healthcare provider should check your blood pressure before starting treatment and regularly during treatment with EFFEXOR XR. If you have high blood pressure, it should be controlled before you start treatment with EFFEXOR XR.
    • Increased risk of bleeding. Taking EFFEXOR XR with aspirin, non-steroidal anti-inflammatory drugs (NSAIDs), or blood thinners may add to this risk. Tell your healthcare provider right away about any unusual bleeding or bruising.
    • Eye problems (angle-closure glaucoma). EFFEXOR XR may cause a certain type of eye problem called angle-closure glaucoma. You may want to undergo an eye examination to see if you are at risk and receive preventative treatment if you are. Call your healthcare provider if you have eye pain, changes in your vision, or swelling or redness in or around the eye.
    • Manic episodes. Manic episodes may happen in people with bipolar disorder who take EFFEXOR XR. Symptoms may include:

      • greatly increased energy
      • severe trouble sleeping
      • racing thoughts
      • reckless behavior
      • unusually grand ideas
      • excessive happiness or irritability
      • talking more or faster than usual
    • Discontinuation syndrome. Suddenly stopping EFFEXOR XR may cause you to have serious side effects. Your healthcare provider may want to decrease your dose slowly. Symptoms may include:
    • Seizures (convulsions).
    • Low sodium levels in your blood (hyponatremia). Low sodium levels can happen during treatment with EFFEXOR XR. Low sodium levels in your blood may be serious and may cause death. Elderly people may be at greater risk for this.
    • Lung problems. Some people who have taken the medicine venlafaxine which is the same kind of medicine as the medicine in EFFEXOR XR have had lung problems. Symptoms of lung problems include difficulty breathing, cough, or chest discomfort. Tell your healthcare provider right away if you have any of these symptoms
    • Sexual problems (dysfunction). Taking selective serotonin reuptake inhibitors (SNRIs), including EFFEXOR XR, may cause sexual problems.

    Do not drive, or operate heavy machinery, or do other dangerous activities until you know how EFFEXOR XR affects you. EFFEXOR XR can make you drowsy.

    You should not drink alcohol during treatment with EFFEXOR XR.

    The most common side effects of EFFEXOR XR include:

    • nausea
    • sleepiness
    • dry mouth
    • male and female sexual problems
    • loss of appetite (anorexia)
    • sweating
    • constipation

    These are not all the possible side effects of EFFEXOR XR. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    INDICATIONS

    EFFEXOR XR (venlafaxine extended-release) capsules are a prescription medicine used to treat adults with a certain type of depression called Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), or Panic Disorder (PD).
    It is not known if EFFEXOR XR is safe and effective for use in children.

    Please see Full Prescribing Information, including BOXED WARNING and Medication Guide.

    EFFEXOR XR SAVINGS CARD TERMS AND CONDITIONS

    By participating in the EFFEXOR XR Savings Offer Program, you acknowledge that you currently meet the eligibility criteria and will comply with the terms and conditions described below:

    • This Savings Offer is not valid for prescriptions that are reimbursed, in whole or in part, by Medicaid, Medicare, TRICARE, Veterans Affairs healthcare, or any other federal or state healthcare program (including any state prescription drug assistance program), or the Government Health Insurance Plan available in Puerto Rico (formerly known as “La Reforma de Salud”)
    • The value of this Savings Offer is limited to $150 per use or the amount of your co-pay, whichever is less
    • This Savings Offer is not valid when the entire cost of your prescription drug is eligible to be reimbursed by your private insurance plans or other health or pharmacy benefit programs
    • You must deduct the savings received under this program from any reimbursement request submitted to your insurance plan, either directly by you or on your behalf
    • Eligible patients may pay a minimum of $4 per monthly prescription fill. By using this Savings Offer, eligible patients may receive a savings of up to $150 per fill off their co-pay or out-of-pocket costs. This Savings Offer is available for a maximum savings of $1,800 per year ($150 per month x 12 months). This Savings Offer may limit your prescription cost to $4, subject to a maximum $150 monthly benefit. Thus, if your co-pay or out-of-pocket cost is more than $150, you will save $150 off of your co-pay or total out-of-pocket costs. [Example: If your co-pay or out-of-pocket costs are $175, you will pay $25 ($175 – $150 = $25).] If your co-pay or out-of-pocket costs are no more than $150, you pay $4. For a mail-order 3-month prescription, your total maximum savings will be $450 ($150 x 3)
    • You must be 18 years of age or older to redeem this Savings Offer
    • Patients who are enrolled in Medicare, Medicaid, or another state or federal healthcare program may use this Savings Offer if paying for the prescription covered by this Savings Offer outside of their government insurance benefit, and no claim is submitted to Medicare, Medicaid, or any federal or state healthcare program. Such patients must not apply any out-of-pocket expenses incurred using this Savings Offer toward any government insurance benefit out-of-pocket spending calculations, such as Medicare Part D true out-of-pocket (TrOOP) costs
    • You are responsible for reporting use of this Savings Offer to any private insurer, health plan, or other third party who pays for or reimburses any part of the prescription filled using this Savings Offer, as may be required. You should not use this Savings Offer if your insurer or health plan prohibits use of manufacturer Savings Offers
    • This Savings Offer is not valid (i) for Massachusetts residents or (ii) for California residents whose prescriptions are covered, in whole or in part, by third-party insurance
    • This Savings Offer is not valid where prohibited by law
    • This Savings Offer is not valid for purchases of prescriptions discounted under the 340B drug pricing program
    • This Savings Offer cannot be combined with any other rebate/coupon, free trial, or similar offer for the specified prescription
    • This Savings Offer will be accepted only at participating pharmacies
    • This Savings Offer is not health insurance
    • This Savings Offer is good only in the U.S. and Puerto Rico
    • This Savings Offer is limited to 1 per person during this offering period and is not transferable
    • This Savings Offer may not be redeemed more than once per 30 days per patient
    • No other purchase is necessary
    • Data related to your redemption of this Savings Offer may be collected, analyzed, and shared with Viatris for market research and other purposes related to assessing Viatris' programs. Data shared with Viatris will be aggregated and de-identified; it will be combined with data related to other Savings Offer redemptions and will not identify you
    • Viatris reserves the right to rescind, revoke, or amend the program without notice
    • No membership fees. This Savings Offer and Program expire on 12/31/2024
    • For help with the EFFEXOR XR Savings Offer, call 1-855-488-0750, visit EFFEXORXR.com, or write: Viatris, P.O. Box 2941, Mission, KS 66201

    If your pharmacy does not participate, you may be able to submit a request for a rebate in connection with this Savings Offer. Pay for your EFFEXOR XR prescription and mail copy of original pharmacy receipt (cash register receipt NOT valid) with product name, date, and amount circled to: EFFEXOR XR Savings Offer, 2250 Perimeter Park Drive, Suite 300, Morrisville, NC 27560. Be sure to include a copy of the front of your EFFEXOR XR Savings Card, your name, and mailing address.

    EFFEXOR XR is available by prescription only.

    Patients should always ask their doctors for medical advice about adverse events.

    You are encouraged to report adverse events related to Viatris products by calling 1-877-446-3679 (U.S. only). If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly. Visit http://www.fda.gov/MedWatch or call 1-800-FDA-1088.

    This site is intended only for U.S. residents. The products discussed in this site may have different product labeling in different countries. The information provided is for educational purposes only and is not intended to replace discussions with a healthcare provider.

    Important Safety Information and Indications
    +-

    What is the most important information I should know about EFFEXOR XR?
    EFFEXOR XR may cause serious side effects, including:

    Increased risk of suicidal thoughts and actions: EFFEXOR XR may increase suicidal thoughts and actions in some children, adolescents, and young adults, especially within the first few months of treatment or when the dose is changed. EFFEXOR XR is not for use in children.

    • Depression or other serious mental illnesses are the most important causes of suicidal thoughts or actions.
    • Pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is started or when the dose is changed.
    • Call your healthcare provider right away to report new or sudden changes in mood, behavior, thoughts, or feelings.
    • Keep all follow-up visits with your healthcare provider as scheduled. Call your healthcare provider between visits as needed, especially if you have concerns about symptoms.

    Call your healthcare provider or get emergency help right away if you or a family member have any of the following symptoms, especially if they are new, worse, or worry you:

    • attempts to commit suicide
    • thoughts about suicide or dying
    • acting aggressive, being angry, or violent
    • acting on dangerous impulses
    • new or worse depression
    • new or worse anxiety
    • panic attacks
    • feeling very agitated or restless
    • new or worse irritability
    • trouble sleeping
    • an extreme increase in activity or talking (mania)
    • other unusual changes in behavior or mood

      Do not take EFFEXOR XR if you:

    • are allergic to venlafaxine hydrochloride, desvenlafaxine succinate, or any of the ingredients in EFFEXOR XR. See the end of this Medication Guide for a complete list of ingredients in EFFEXOR XR.
    • take a Monoamine Oxidase Inhibitor (MAOI)
    • have stopped taking an MAOI in the last 14 days
    • are being treated with the antibiotic linezolid or intravenous methylene blue

    Ask your healthcare provider or pharmacist if you are not sure if you take an MAOI, including MAOIs such as linezolid or intravenous methylene blue.

    Do not start taking an MAOI for at least 7 days after you stop treatment with EFFEXOR XR.

    Before taking EFFEXOR XR tell your healthcare provider about all your medical conditions and all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

    EFFEXOR XR and other medicines may affect each other causing possible serious side effects.

    EFFEXOR XR may affect the way other medicines work and other medicines may affect the way EFFEXOR XR works.

    Do not start or stop any other medicines during treatment with EFFEXOR XR without first talking to your healthcare provider.

    EFFEXOR XR may harm your unborn baby. Tell your healthcare provider if you are pregnant, plan to become pregnant, or think you are pregnant during treatment with EFFEXOR XR.

     

    EFFEXOR XR may cause serious side effects, including:

    • See, “What is the most important information I should know about EFFEXOR XR?”
    • Serotonin syndrome. Taking EFFEXOR XR can cause a potentially life-threatening problem called serotonin syndrome. The risk of developing serotonin syndrome is increased when EFFEXOR XR is taken with certain other medicines. Stop taking EFFEXOR XR and call your healthcare provider or go to the nearest hospital emergency room right away if you have any of the following signs and symptoms of serotonin syndrome:
      • agitation
      • seeing or hearing things that are not real (hallucinations)
      • confusion
      • coma
      • fast heartbeat
      • changes in blood pressure
      • dizziness
      • sweating
      • flushing
      • high body temperature (hyperthermia)
      • tremors, stiff muscles, or muscle twitching
      • loss of coordination
      • seizures
      • nausea, vomiting, diarrhea
    • Increases in blood pressure. Your healthcare provider should check your blood pressure before starting treatment and regularly during treatment with EFFEXOR XR. If you have high blood pressure, it should be controlled before you start treatment with EFFEXOR XR.
    • Increased risk of bleeding. Taking EFFEXOR XR with aspirin, non-steroidal anti-inflammatory drugs (NSAIDs), or blood thinners may add to this risk. Tell your healthcare provider right away about any unusual bleeding or bruising.
    • Eye problems (angle-closure glaucoma). EFFEXOR XR may cause a certain type of eye problem called angle-closure glaucoma. You may want to undergo an eye examination to see if you are at risk and receive preventative treatment if you are. Call your healthcare provider if you have eye pain, changes in your vision, or swelling or redness in or around the eye.
    • Manic episodes. Manic episodes may happen in people with bipolar disorder who take EFFEXOR XR. Symptoms may include:
      • greatly increased energy
      • severe trouble sleeping
      • racing thoughts
      • reckless behavior
      • unusually grand ideas
      • excessive happiness or irritability
      • talking more or faster than usual
    • Discontinuation syndrome. Suddenly stopping EFFEXOR XR may cause you to have serious side effects. Your healthcare provider may want to decrease your dose slowly. Symptoms may include:
    • Seizures (convulsions).
    • Low sodium levels in your blood (hyponatremia). Low sodium levels can happen during treatment with EFFEXOR XR. Low sodium levels in your blood may be serious and may cause death. Elderly people may be at greater risk for this.
    • Lung problems. Some people who have taken the medicine venlafaxine which is the same kind of medicine as the medicine in EFFEXOR XR have had lung problems. Symptoms of lung problems include difficulty breathing, cough, or chest discomfort. Tell your healthcare provider right away if you have any of these symptoms
    • Sexual problems (dysfunction). Taking selective serotonin reuptake inhibitors (SNRIs), including EFFEXOR XR, may cause sexual problems.
     

    Do not drive, or operate heavy machinery, or do other dangerous activities until you know how EFFEXOR XR affects you. EFFEXOR XR can make you drowsy.

    You should not drink alcohol during treatment with EFFEXOR XR.

    The most common side effects of EFFEXOR XR include:

    • nausea
    • sleepiness
    • dry mouth
    • male and female sexual problems
    • loss of appetite (anorexia)
    • sweating
    • constipation

    These are not all the possible side effects of EFFEXOR XR. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Indications
    EFFEXOR XR (venlafaxine extended-release) capsules are a prescription medicine used to treat adults with a certain type of depression called Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), or Panic Disorder (PD).

    It is not known if EFFEXOR XR is safe and effective for use in children.

    Please see Full Prescribing Information, including BOXED WARNING and Medication Guide.

    What is the most important information I should know about EFFEXOR XR?
    EFFEXOR XR may cause serious side effects, including:

    Increased risk of suicidal thoughts and actions: EFFEXOR XR may increase suicidal thoughts and actions in some children, adolescents, and young adults, especially within the first few months of treatment or when the dose is changed. EFFEXOR XR is not for use in children.

    • Depression or other serious mental illnesses are the most important causes of suicidal thoughts or actions.
    • Pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is started or when the dose is changed.
    • Call your healthcare provider right away to report new or sudden changes in mood, behavior, thoughts, or feelings.
    • Keep all follow-up visits with your healthcare provider as scheduled. Call your healthcare provider between visits as needed, especially if you have concerns about symptoms.

    Call your healthcare provider or get emergency help right away if you or a family member have any of the following symptoms, especially if they are new, worse, or worry you:

    • attempts to commit suicide
    • thoughts about suicide or dying
    • acting aggressive, being angry, or violent
    • acting on dangerous impulses
    • new or worse depression
    • new or worse anxiety
    • panic attacks
    • feeling very agitated or restless
    • new or worse irritability
    • trouble sleeping
    • an extreme increase in activity or talking (mania)
    • other unusual changes in behavior or mood

      Do not take EFFEXOR XR if you:

    • are allergic to venlafaxine hydrochloride, desvenlafaxine succinate, or any of the ingredients in EFFEXOR XR. See the end of this Medication Guide for a complete list of ingredients in EFFEXOR XR.
    • take a Monoamine Oxidase Inhibitor (MAOI)
    • have stopped taking an MAOI in the last 14 days
    • are being treated with the antibiotic linezolid or intravenous methylene blue

    Ask your healthcare provider or pharmacist if you are not sure if you take an MAOI, including MAOIs such as linezolid or intravenous methylene blue.

    Do not start taking an MAOI for at least 7 days after you stop treatment with EFFEXOR XR.  

    Before taking EFFEXOR XR tell your healthcare provider about all your medical conditions and all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

    EFFEXOR XR and other medicines may affect each other causing possible serious side effects.

    EFFEXOR XR may affect the way other medicines work and other medicines may affect the way EFFEXOR XR works.

    Do not start or stop any other medicines during treatment with EFFEXOR XR without first talking to your healthcare provider.

    EFFEXOR XR may harm your unborn baby. Tell your healthcare provider if you are pregnant, plan to become pregnant, or think you are pregnant during treatment with EFFEXOR XR.

     

    EFFEXOR XR may cause serious side effects, including:

    • See, “What is the most important information I should know about EFFEXOR XR?”
    • Serotonin syndrome. Taking EFFEXOR XR can cause a potentially life-threatening problem called serotonin syndrome. The risk of developing serotonin syndrome is increased when EFFEXOR XR is taken with certain other medicines. Stop taking EFFEXOR XR and call your healthcare provider or go to the nearest hospital emergency room right away if you have any of the following signs and symptoms of serotonin syndrome:
      • agitation
      • seeing or hearing things that are not real (hallucinations)
      • confusion
      • coma
      • fast heartbeat
      • changes in blood pressure
      • dizziness
      • sweating
      • flushing
      • high body temperature (hyperthermia)
      • tremors, stiff muscles, or muscle twitching
      • loss of coordination
      • seizures
      • nausea, vomiting, diarrhea
    • Increases in blood pressure. Your healthcare provider should check your blood pressure before starting treatment and regularly during treatment with EFFEXOR XR. If you have high blood pressure, it should be controlled before you start treatment with EFFEXOR XR.
    • Increased risk of bleeding. Taking EFFEXOR XR with aspirin, non-steroidal anti-inflammatory drugs (NSAIDs), or blood thinners may add to this risk. Tell your healthcare provider right away about any unusual bleeding or bruising.
    • Eye problems (angle-closure glaucoma). EFFEXOR XR may cause a certain type of eye problem called angle-closure glaucoma. You may want to undergo an eye examination to see if you are at risk and receive preventative treatment if you are. Call your healthcare provider if you have eye pain, changes in your vision, or swelling or redness in or around the eye.
    • Manic episodes. Manic episodes may happen in people with bipolar disorder who take EFFEXOR XR. Symptoms may include:
      • greatly increased energy
      • severe trouble sleeping
      • racing thoughts
      • reckless behavior
      • unusually grand ideas
      • excessive happiness or irritability
      • talking more or faster than usual
    • Discontinuation syndrome. Suddenly stopping EFFEXOR XR may cause you to have serious side effects. Your healthcare provider may want to decrease your dose slowly. Symptoms may include:
    • Seizures (convulsions).
    • Low sodium levels in your blood (hyponatremia). Low sodium levels can happen during treatment with EFFEXOR XR. Low sodium levels in your blood may be serious and may cause death. Elderly people may be at greater risk for this.
    • Lung problems. Some people who have taken the medicine venlafaxine which is the same kind of medicine as the medicine in EFFEXOR XR have had lung problems. Symptoms of lung problems include difficulty breathing, cough, or chest discomfort. Tell your healthcare provider right away if you have any of these symptoms
    • Sexual problems (dysfunction). Taking selective serotonin reuptake inhibitors (SNRIs), including EFFEXOR XR, may cause sexual problems.
     

    Do not drive, or operate heavy machinery, or do other dangerous activities until you know how EFFEXOR XR affects you. EFFEXOR XR can make you drowsy.

    You should not drink alcohol during treatment with EFFEXOR XR.

    The most common side effects of EFFEXOR XR include:

    • nausea
    • sleepiness
    • dry mouth
    • male and female sexual problems
    • loss of appetite (anorexia)
    • sweating
    • constipation

    These are not all the possible side effects of EFFEXOR XR. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Indications
    EFFEXOR XR (venlafaxine extended-release) capsules are a prescription medicine used to treat adults with a certain type of depression called Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), or Panic Disorder (PD).

    It is not known if EFFEXOR XR is safe and effective for use in children.

    Please see Full Prescribing Information, including BOXED WARNING and Medication Guide.

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    EFFEXOR XR is a registered trademark of Viatris Specialty LLC, a Viatris Company. VIATRIS and the Viatris logo are trademarks of Mylan Inc., a Viatris Company.

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